Home » What is Parvovirus B19, the Highly Contagious Virus the CDC Warned About?

What is Parvovirus B19, the Highly Contagious Virus the CDC Warned About?

by AbuBakr
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parvovirus B19
This week, the Centers for Disease Control and Prevention (CDC) issued a health advisory following an uptick in cases of parvovirus B19. According to the CDC, “In the first quarter of 2024, public health authorities in 14 European countries reported unusually high numbers of parvovirus B19 cases.” The alert also noted increased activity in the U.S. Here’s what you need to know about this contagious virus, including its transmission, symptoms, and at-risk groups.

What is Parvovirus B19?

Parvovirus B19 is a seasonal virus primarily spread through respiratory droplets from coughing and sneezing, whether the person is symptomatic or asymptomatic. Known as “fifth disease,” it is part of a group of childhood illnesses characterized by rash, such as measles and scarlet fever. A blood test can detect antibodies to parvovirus B19, which indicate whether a person is currently infected, has been infected in the past, or is immune.

How Does Parvovirus B19 Spread?

The virus is highly transmissible. The CDC reports that 50% of people exposed in a household setting become infected, while 20% to 50% of individuals in school settings are affected during outbreaks. Previous infections provide some protection, with antibodies likely preventing future infections. By age 20, about 50% of adults have these antibodies, and this number rises to 70% by age 40. Transmission can also occur from a mother to her fetus during pregnancy and through blood or plasma transfusions, though the latter is extremely rare.

What Are the Symptoms of Parvovirus B19?

Symptoms of parvovirus B19 are generally mild and can include:
  • Fever
  • Headache
  • Cough
  • Sore throat
  • Rashes
  • Joint pain
Many individuals with parvovirus B19 may not exhibit any symptoms. For those who do, symptoms occur in two phases. The first phase, beginning about a week after infection, includes fever, muscle pain, sore throat, and fatigue. This phase lasts approximately five days and is when individuals are most contagious, as viral loads in respiratory secretions peak. The second phase, occurring about seven to ten days later, often features a distinctive facial rash in children, sometimes followed by joint pain and/or a mottled body rash. In adults, the second phase typically involves joint pain and a rash on the torso. By the time a rash appears, the person is usually no longer contagious.

How is Parvovirus B19 Treated?

There is no vaccine or specific treatment for parvovirus B19. Most individuals recover without medical intervention. Severe complications, such as myocarditis, hepatitis, or encephalitis, are rare. For pregnant women, most cases resolve without serious consequences. However, there is a 5% to 10% risk of fetal anemia or miscarriage if the mother contracts the virus between weeks 9 and 20 of pregnancy. Treatment for pregnant women focuses on monitoring and managing severe fetal anemia. For healthy individuals, parvovirus B19 generally resolves on its own. However, the CDC advises pregnant women and those with compromised immune systems—such as individuals with chronic hemolytic blood disorders like sickle cell disease, thalassemia, and hereditary spherocytosis—to seek medical care if they experience symptoms or have been exposed to someone with confirmed or suspected parvovirus B19.

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